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MOTS-c is a mitochondrial-derived peptide that regulates metabolic pathways and helps with the proper utilization of fatty acids for energy

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Trials showed good tolerability and placebo-like side effect profile

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A recent overview article summarizing AOD 9604 research notes that in isolated chondrocyte cultures, AOD 9604 has been reported to promote proteoglycan and collagen production , and may influence differentiation of adipose-derived mesenchymal stem cells toward osteogenic lineages suggesting a possible role as a tool to study cartilage and bone matrix biology

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