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References Yudkoff M

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In addition, the presence of many lysine residues in antibodies often results in heterogeneous ADC products, necessitating site-specific conjugation technologies to produce homogeneous ADCs

[PubMed] [Google Scholar] Aman Y., Qiu Y., Tao J., Fang E

This phenomenon arises when atoms in a bond have differing electronegativities, causing electrons to be pulled closer to the more electronegative atom

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