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Women planning pregnancy should discontinue use at least 2 months before attempting conception to allow for complete medication washout
**Kidney Function:** Weight Management Solutions/Programs may affect kidney function, and careful monitoring is important, especially in individuals with pre-existing kidney conditions
Subsequent dose adjustments may be made based on how your body responds to the medication, typically with another increase after an additional four weeks under medical supervision
As a phase 2 dose-ranging study, this trial was not designed to provide the definitive efficacy evidence required for regulatory submission

The daily schedule Fasting window: 8pm to 12pm (16 hours) Eating window: 12pm to 8pm (8 hours) 12:00pm - Break fast with Meal 1 (protein-first) 3:00pm - Meal 2 or substantial snack (protein-forward) 6:30pm - Meal 3 (final meal of the day) 7:30pm - Optional protein shake if targets not met 8:00pm - Eating window closes During fasting window: water, black coffee, plain tea, electrolytes (sodium, potassium, magnesium) without calories

doi: 10.1073/pnas.0308291101 212 MeyerTEKovcsSJEhsaniAAKleinSHolloszyJOFontanaL