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Cell stem cell 13 , 270283, doi: 10.1016/j.stem.2013.08.002 (2013)

A "no" to all three keeps the bottle in use

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SOCS proteins bind to phosphotyrosine residues on the GHR or JAK2 and suppress GH signaling by inhibiting JAK2 activity and competing with STATs for binding on the GHR