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10.1177/23800844231196884 38 HartlD.GaggarA.BrusciaE.HectorA.MarcosV.JungA.et al (2012)

Advances in deep brain stimulation: from mechanisms to applications

100 Furthermore, the combination of single-cell RNA-sequencing and genotyping from bone marrow samples of 16 AML patients demonstrated that FLT3- ITD-mutated cells were enriched in the cell populations with undifferentiated HSC/progenitor-like cell signatures, suggesting that FLT3 -ITD confers a strong differentiation block

HO-1 is a key mediator of ferroptosis and plays an important role in the development of various diseases (Lei et al., 2019)