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Figure 1 2 The role of innate immunity in vitiligo The innate immunity system serves as the bodys first line of defense, capable of recognizing and responding to pathogens without prior exposure ( + T cells, the principal executors of melanocyte destruction ( 3 Factors triggering innate immune activation in vitiligo Innate immune activation in vitiligo is triggered by a variety of factors, including environmental, genetic, and endogenous elements

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Histological alterations and molecular mechanisms such as oxidative stress, induction of ferroptosis, and impaired mitochondrial function offer deeper insight into the pathogenesis of plastic-induced lung injury

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