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Phenothiazine normalizes the NADH/NAD(+) ratio, maintains mitochondrial integrity and protects the nigrostriatal dopamine system in a chronic rotenone model of Parkinsons disease
In addition H 2 O 2 drives the GSH/GSSG balance towards GSSG, which inhibits MAT I and MAT III

doi: 10.1016/j.etap.2016.06.008

Redox status of plasma coenzyme Q10 indicates elevated systemic oxidative stress in Parkinsons disease

Cell Nanomed