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The beneficial components in apples vary in the type and amount that can be found within the cultivars or varieties from different countries, regions, or continents
M.ProcterJ
While existing trials are focusing on repurposed agents such as the diuretic bumetanide, the vasopressin 1a receptor agonist, balovaptan and the GABA B receptor agonist, baclofen, modulation of histamine receptors may be an additional viable target in helping to ameliorate difficulties associated with NDDs
Caraci, Filippo, et al., 2011
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