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TNF-a is produced by activated macrophages, T and B lymphocytes, natural killer cells, astrocytes, endothelial cells, smooth muscle cells, some tumor cells, and epithelial cells

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IC50 at 48 hours ranged from 10.8 to 85.5 nM in T-ALL and from 14.7 to 101.1 nM in BCP-ALL

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10.1016/j.snb.2023.134819 209 YuX.HeL.PentokM.YangH.YangY.LiZ.et al (2019)