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The cells were then washed three times with serum-free DMEM and incubated in 0.5 ml serum-free DMEM for 6 h at 37 C
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To note, NRF2 regulates BRCA1 by the presence of an ARE sequence in BRCA1 promoter, creating a positive-feedback loop, with an increase of both transcripts [175]
We have co-crystallized PrfA bound to an intact 28-bp complementary dsDNA (plus 1-nt 5 overhang at either end) and solved the structure of the binary complex at 2.93 resolution (X-ray statistics in Table S1)
doi: 10.1002/ana.10828
