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The rs1050450 (Pro198Leu) polymorphism of glutathione peroxidase 1 (GPx1), a selenium-dependent antioxidant enzyme, may modulate selenium status and enzymatic activity

This in turn may exhibit positive action on wound healing processes.(5)TB-500 also seems to amplify the presence of microRNA-146a (miR-146a), which may act as a repressive regulator for certain cellular signaling routes such as those related to the activity of two inflammation-related cytokines called L-1 receptor-linked kinase 1 (IRAK1) and tumor necrosis factor receptor-linked factor 6 (TRAF6)

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