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Ferroptosis and endometriosis The crosstalk between ferroptosis and inflammation Endometriosis is a chronic inflammatory disease that is closely related to inflammation and the immune response

3.3.3 Cooperation and competition between SMURF2 and other ubiquitination systems in ferroptosis regulation The ubiquitinproteasome system (UPS) consists of various E1, E2, and E3 enzymes, and different E3 ligases can act cooperatively or antagonistically in ferroptosis regulation by targeting the same or different substrates

Prx6 directly binds selenide or selenol intermediates at its catalytic cysteine 47 in the presence of GSH

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Co-immunprecipitated proteins were analyzed by Western Blotting (WB) using anti-CLCF1 or anti-ApoE mAbs (R&D systems, Cedarlane) and horseradish peroxidase (HRP)-labelled secondary Abs