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[DOI] [PubMed] [Google Scholar] 51.Hollanders J, et al

Mechanism Investigation: GHK-Cus mechanisms are diverse and include: Copper delivery to cells and copper-dependent enzyme activation Gene expression regulation (hundreds of genes affected) TGF- signaling pathway modulation MMP expression regulation via transcriptional mechanisms Antioxidant enzyme expression upregulation Inflammatory mediator production modulation Stem cell differentiation influence Direct antioxidant activity through copper redox chemistry The peptides small size belies its extensive biological activities, likely mediated through multiple mechanisms operating in parallel

The irony, as you point out, is that this same rigidness does not apply to other medications that can be prescribed in a more flexible manner

IV therapy delivers glutathione directly into your bloodstream , bypassing the gut for maximum absorption and effect

doi: 10.1186/2045-5380-1-11