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Diabetes Care (2011) 34:261423
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[DOI] [PubMed] [Google Scholar] 256
Um34 promotes metastasis in vivo To determine if FTSJ1 and therefore tRNA Sec Um34 modification are necessary for metastasis, we transplanted FTJS1 KO A375 melanoma cells co-expressing luciferase subcutaneously into immunocompromised mice and measured both primary tumor growth as well as overall metastatic burden in the organs
