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This article systematically reviews the mechanisms and signaling pathways of ferroptosis in CRC, the role of ferroptosis within the tumor microenvironment, and the progress in research on ferroptosis in reducing drug resistance

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Non-compliance with venesection is more common in the maintenance phase and such patients are at risk of reaccumulating iron and associated complications [145]

For instance, in triple-negative breast cancer cells, methionine restriction rapidly and transiently increases intracellular reactive oxygen species levels, accompanied by a swift depletion of glutathione and a decline in the ratio of reduced to oxidized glutathione (66)

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