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In a randomized, single-center, double-blind, placebo-controlled clinical trial, the oral administration of 600 mg/kg ALA twice daily for over 6 months resulted in significant symptomatic improvements in DPN patients
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In addition, nucleic acids face challenges relating to stability and immunogenicity in vivo [31]
In the absence of critical cofactors synthesis of the master antioxidant glutathione from Hcy cannot proceed
10.3390/biom10020311 12 ChangJ.XuZ
(Huanglian) (Wang et al., 2021
