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BSO decreases GSH synthesis and DEM, a weak electrophile forms DEM-GSH adducts, although DEM may not be absolutely specific to GSH [27]

In the present study, we confirmed the role of oxidative stress and ferroptosis in SAP

Treatment of HL-1 cells with the broad-spectrum PKC inhibitor, BIM1, led to a significant decrease in Ect2 activity compared with DMSO vehicle treatment (Fig 5A and 5A)

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Liang, Y., Zhou, R., Fu, X., Wang, C

USP8 promotes gemcitabine resistance of pancreatic cancer via deubiquitinating and stabilizing Nrf2