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Although glutamate contributes to TCA cycle anaplerosis, its nitrogen is preferentially channeled into NEAA biosynthesis in rapidly proliferating cancer cells, reflecting a nitrogen-sparing strategy

Psychiatry 2020 , 11

Alternatively, the new drug can be tested against placebo as an additional therapy to NA
Lazzara V et al

The generation of ROS is induced by extracellular and intracellular stimuli as well as during mitochondrial oxidative metabolism, the primary source of endogenous ROS [15,16,17]

Sci Rep 2022
