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Although, these effects are not extensively studied in the pancreatic -cells, the bidirectional interaction of ceramide and ROS/RNS may also be involved in the apoptotic cascades in -cells

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[12] Most importantly, researchers have successfully genetically engineered GSTZ1 to mimic one of the most significant antioxidant enzymes, glutathione peroxidase (GPX)

[DOI] [PMC free article] [PubMed] [Google Scholar] 487.Booth S.L., Al Rajabi A

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