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To prevent the downstream effect of zonulin binding to its receptors after intestinal gliadin exposure, it is proposed that LA antagonizes the zonulin pathway by competitively inhibiting zonulin binding to target receptors, but further mechanistic studies are needed in order to support this proposal (Fig

Acc Chem Res 48(5):13321339

Requires careful patient monitoring (renal function, G6PD status) before initiating mega-dose infusions

Ma WX, Li CY, Tao R, Wang XP, Yan LJ

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A., Gonzalez-Cantu, J
