l-carnitine and alpha lipoic acid dosage Solaray Aceteyl Acid, 60 Vegetarian Capsules Source Naturals Acetyl L-Carnitine &

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List of the abbreviations PRP: Platelet-Rich Plasma MRI: Magnetic Resonance Imaging ACL: Anterior Cruciate Ligament NRS: Numerical Rating Scale KOOS: Knee Injury and Osteoarthritis Outcome Score TLKSS: Tegner Lysholm Knee Scoring Scale VAS: Visual Analog Scale SF-36: RAND-36 (Short Form 36) IKDC: International Knee Documentation Committee IL: Interleukin TGF-: Transforming Growth Factor Beta PDGF: Platelet-Derived Growth Factor IGF: Insulin-like Growth Factor VEGF: Vascular Endothelial Growth Factor EGF: Epidermal Growth Factor -FGF: Basic Fibroblast Growth Factor NSAIDs: Non-steroidal anti-inflammatory Drugs Authors Contributions Both authors AEZ and JY equally contributed to the project

PA treatment produced a statistically significant decrease in liver enzymes and an increase in the albumin level compared to the APAP group

Zhong W, Yan T, Lim R, Oberley LW

While the study reported positive effects on cerebrospinal fluid biomarkers of neuroinflammation and neurodegeneration, it did not meet its primary clinical efficacy endpoint, highlighting the difficulty of translating biological signals into measurable clinical benefits in a heterogeneous patient population (65)