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In addition to the endogenous cellular pathways, recent studies have also investigated the role of the gut microbiome in affecting NAD + levels

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B.et al (2001)

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54,55 Thus, age-related compromises in the activity of antioxidant enzymes, diminished concentrations of antioxidants, and reduced activity of protein editing-capacities lead to attenuated protection against oxidative insults

In addition, consuming Arg and other AA-rich NS, including Cit, BCAA, and fructose, decreased oxygen intake during moderate-intensity exercise, reduced plasma lactate production during exercise, and improved exercise tolerance during high-intensity exercise [32,35]