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Trained immunity: a memory for innate host defense

With a view to the role of oxidative stress on HT development, products rich in antioxidants should be implemented (e.g., fruit, vegetables, herbs and spices, mostly with a high concentration of polyphenols)

While we cannot disregard the possibility of some remaining effects of relaxation time differentials, we note that our results are metabolite-specific, while systematic between-group differences in relaxation times would likely impact all metabolite concentrations equally

Its levels decline with age, and research focuses on wound healing, collagen synthesis, and anti-inflammatory pathways

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The enzyme complex is also regulated by energy charge, the NAD + /NADH ratio, and effector activity of substrates and products