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The result is increasing levels of intoxication
They achieved this by blocking the reabsorption of uric acid at the proximal tubule of the kidney via the inhibition of the urate transporter 1 (URAT1)
Dhurat et al

Solution NMR mapping of water-accessible residues in the transmembrane beta-barrel of OmpX

Exact number not reported but estimated from differential expression results or inferred from supplementary material
