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While some commenters stated that the Brief Interview for Mental Status (BIMS) and Confusion Assessment Method (CAM) measures already collected were sufficient, others objected to their use for quality measurement noting that a patient's BIMS score is not expected to improve with treatment

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A small amount (approximately 1% of the total amount ingested) is absorbed by simple diffusion, but this mechanism is adequate only with very large doses

This decrease is associated with the cessation of B12 injections at 6 weeks indicating injections may be effective only short-term

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