michael-type acceptor reactivity toward glutathione Thiol-based addition. A systematic evaluation of its controlling factors Nucleophilicity of Glutathione: A Link
Description
This may be due to the rapid metabolization of GSH during the collection, freezing, and fixation interval, as demonstrated using mouse brain (Miller et al., 2009)

On the other hand, depletion or elevation of GSH can increase bacterial vulnerability, which can be exploited in antibiotic therapy

And they're at higher risk for atrophic gastritis

5-Fluorouracil: Mechanisms of Action and Clinical Strategies

Gliotoxin was firstly isolated from A
H.YoonY
