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Burning feet syndrome formally called Grierson-Gopalan syndrome after the physicians who first described it refers to a constellation of symptoms: persistent burning, heat, and sometimes tingling or aching in the feet, characteristically worse at night and partially relieved by cool surfaces or cold water

387 Urate oxidase catalyzes the breakdown of uric acid into 5-hydroxyisourate, which subsequently undergoes spontaneous degradation to allantoin without enzymatic assistance

Ng, Office of Occupational Health, World Health Organization, Geneva, Switzerland Dr G