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(2024, November 14)

This mechanism would potentiate total body carnitine deficiency and warrants further pharmacometabolomic study to confirm

Following phenotype onset, tamoxifen was administered systemically, removing the loxP- STOP- loxP cassette and restoring Mecp2 expression to 80% of normal levels

This proliferative halt may indirectly reduce basal levels of cellular anabolism and reactive oxygen species (ROS) generation, thereby enhancing resistance to ferroptosis (108)