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The compound is best known as an inhibitor of nicotinamide Nmethyltransferase (NNMT), an enzyme implicated in adipose tissue energy handling and nicotinamide adenine dinucleotide (NAD+) turnover.
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So far, drugs with cardioprotective effects have included ACE inhibitors and ARBs, statins, antiplatelet drugs, and beta-blockers
Zhao Y, et al
