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Although the exact cause of AD is not yet fully understood, it is becoming evident that oxidative stress plays a key role in the pathogenesis of the disease leading to neuronal cell death

Recent structural studies have shown that phosphate molecules bind to the GTP site

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[DOI] [PubMed] [Google Scholar] 63.Yakut M., Ustun Y., Kabacam G., Soykan I

This observation suggests that AgRP neurons are unable to appropriately sense food deprivation without GH signaling

Beta-hydroxybutyrate was shown to bind receptors in the brain, heart, and liver where it enhances mitochondrial function [87]