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53 HendriksD.PagliaroA.AndreattaF.MaZ.van GiessenJ.MassaliniS.et al (2024)

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Deciphering the reversible glutaredoxin-dependent redox reactions of roGFP2 therefore not only closes a gap in our knowledge of glutaredoxin catalysis but also facilitates the intrepretation of roGFP2 responses from redox measurements and mechanistic analyses in vivo

For in vivo studies, we administered lactate via intraperitoneal injection at a dose of 800 mg/kg, a concentration previously demonstrated to be non-lethal, without inducing acidosis or severe inflammatory side effects 61,62,63

doi: 10.1023/a:1022238706604