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Vitamin E & -carotene (fat soluble), for example, protect against free radicals targeting the inner layer of the cell membrane, while vitamin C (water soluble) protects only the outer layer

For instance, Mardikian et al [69] reported the occurrence of some mild side-effects between 1200, 2400 and 3600 mg/day oral doses of NAC, lying in parallel with the findings of Berk et al [70,71] who evaluated a daily dose of 2 g of NAC (1000 mg twice daily) and also perceived some mild adverse effects

Berzuini A, Bianco C, Paccapelo C, Bertolini F, Gregato G, Cattaneo A, et al

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