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W.BakshiM.SherametiI.DongS.ReicheltM.OelmllerR.et al (2016)

AMPK is a conserved and powerful energy sensor that plays a major role in regulating cellular energy homeostasis ( The synergic action is reached with the carbohydrates plant-derived peptides co-administered with the carbohydrate: on the one hand, the carbohydrates supply the needed substrates of glucose, while inducing insulin secretion by insulin action, activation of glycogen synthase and blocking of glycogen phosphorylase, on the other, plant-derived peptides can also further promote the insulin sensitivity for the sake of enhancing efficiency for glycogen storage ( 7.2 Improvement of lactate metabolism Enhancing lactate metabolism plays a pivotal role in relieving exercise-related fatigue and optimizing sport performance and endurances and can mainly be accomplished by the activity augmentation of lactate dehydrogenase (LDH), the enzyme that facilitates the interconversion of lactate to pyruvate (and further) into the tricarboxylic acid (TCA) cycle for the generation of metabolic energy

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Neuroinflammation is a contributing factor to these neurological complications [65,66]