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Spicatoside A, a steroidal saponin discovered to be present in the Liriope platyphylla extract, induces neurite outgrowth in PC12 cells and NGF synthesis in astrocytes via the TrkA receptor-mediated activation of PI3-kinase and ERK1/2, which controls long-term potentiation and neuronal activity [138]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 327.Antonschmidt L., Matthes D., Dervisoglu R., Frieg B., Dienemann C., Leonov A., Nimerovsky E., Sant V., Ryazanov S., Giese A., et al

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