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[DOI] [PubMed] [Google Scholar] 27.Gomes M.B., Negrato C.A

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THF-dependent demethylases transfer the methyl group non-oxidatively to THF [27], whereas ROs and P450s utilize NAD(P)H as a cofactor to oxidize the methyl group into formaldehyde [26]

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This would remove an enormous financial and time burden from the NHS, and GP Practices and would allow the panic to, at least partially, subside in hundreds of thousands of people in the UK

and truly translating cutting-edge technologies such as PROTAC-ADCs and siRNA-ADCs into clinical practice and real-world cohorts to form an interdisciplinary closed-loop validation