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The principal mechanism involves detoxification process in liver

The fumarate component may contribute to the compound's stability and bioavailability

For example, the LDH levels were elevated in the rat and mouse models of EIF treated with different doses of tea polyphenols (Du, 2012

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Summary: Amino acids, particularly L-arginine and L-citrulline, may provide modest benefits for mild to moderate erectile dysfunction, but evidence is mixed and they are not recommended as first-line treatment in UK guidance

(2005) Ethanol physical dependence is accompanied by up-regulated expression of L-type high voltage-gated calcium channel alpha1 subunits in mouse brain