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Culture and differentiation of primary human bronchial epithelial cells (phBEC) Normal primary human bronchial epithelial cells (phBEC) from three healthy donors were obtained from Lonza (Wokingham, UK), cultured in BEGM medium (Lonza) and differentiated at the air-liquid interface (ALI) in PneumaCult-ALI medium (Stemcell Technologies, Cologne, Germany) for up to 2833 days as described previously 67

1 Wilding JPH, et al

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Lack of FDA Approval and Regulation One of the most pressing issues with BPC-157 is its lack of approval by the Food and Drug Administration (FDA)