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Moreover, the abundance of bacteria carrying bile salt hydrolase and bile acid inducible enzyme in the gut microbiota of IBD patients, such as Firmicutes , Ruminococcaceae , Lachnospiraceae , and Eubacterium , is reduced

Figure 1 ALC reduced plasma TC and LDL-C levels in C57BL/6J mice fed a high-cholesterol diet Building upon the clinical observations, among the differential plasma metabolites of patients with hyperlipidemia, ALC was significantly downregulated and negatively correlated with plasma LDL-C

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McKim, J

Kaempferol stimulates gene expression of low-density lipoprotein receptor through activation of Sp1 in cultured hepatocytes

Cell supernatant was collected from each group, and the levels of IL-1, IL-6, TNF-, IL-8, and IL-10 were determined by ELISA