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Description

Biomolecules 9, 34

This includes the use of advanced analytical techniques (e.g., liquid chromatography-mass spectrometry) to quantify TCM components and their metabolites in plasma, gut, and liver tissues, as well as the integration of pharmacokinetic and pharmacodynamic data to establish doseresponse relationships

This study demonstrated that metabolomics analysis before drug exposure could shed light on the degree of drug-induced hepatotoxicity, a common side effect of acetaminophen [86]

Acknowledgements This work was supported by the Zhejiang Provincial Natural and Science Foundation of China under Grant (LD22H310004), Zhejiang Provincial Natural and Science Foundation (LQN25C070001), Zhejiang Sci-Tech University Research Start-up Fund (24042191-Y)