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They have demonstrated efficacy in alleviating pain associated with diabetic neuropathy, neuralgia, and low back pain, as well as promoting nerve conduction, making them beneficial for a variety of neurological and pain-related conditions

Anyone taking methyl-donor-sensitive medications (some psychiatric drugs, methotrexate, methylated B-vitamin protocols at high doses): NNMT shares the methyl donor SAM, so theoretical interactions exist

Most people get enough B12 from meat, fish, eggs, and dairy

For maximum effectiveness in androgenetic alopecia, combining GHK-Cu with DHT blockers (finasteride, dutasteride, or natural alternatives like saw palmetto) addresses both the cause and the symptoms

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