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We show that Pin1 requires these phosphorylation events to act negatively on FOXO4 transcriptional activity
doi:10.21926/obm.geriatr.1803009

It eventually results in reduced signal transmission, especially through the RAF-MEK-ERK/MAP pathway

Multiple studies have established a connection between disruptions in the microbiota composition, driven by abnormalities in bacterial metabolites, and the dysregulation of immunological responses and changes in the gut-brain axis (Mirzaei et al., 2021)

While transgenic up-regulation of glutathione synthesis has been reported to increase heavy metal tolerance, effects of overexpressing PCS have been less clear (Zhu et al., 1999a,b

Selenium is an essential trace mineral that plays a key role in antioxidant defense, immune function, thyroid hormone metabolism and cellular health
