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Zonisamide produces weight loss in psychotropic drug-treated psychiatric outpatients

These modifications include DNA methylation, post-translational histone modifications, chromatin rearrangement, and non-coding RNAs (ncRNAs) [118] (Figure 3)

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Interestingly, the depletion of zinc ion can significantly upregulate the expression levels of gliotoxin biosynthesis, especially that of the gliZ positive regulator, which is a Zn 2 -Cys 6 binuclear transcriptional factor