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[DOI] [PubMed] [Google Scholar] 1606.Shibata T, Yamada K, Watanabe M, Ikenaka K, Wada K, Tanaka K, Inoue Y

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Numerous studies further confirmed that extracts and active monomers of Ligustri Lucidi Fructus regulated the differentiation and function of osteoblasts (Wu et al., 2021
In macrophages, HCA2 couples to Gi/o-type G proteins that, via protein kinase A (PKA) or G, can inhibit NF-B and reduces cytokine expression (152), whereas in neutrophils HCA2 via Gi/o reduces cAMP favoring apoptosis through the pro-apoptotic protein BAD (147)

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