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Ortega MA, Fraile-Martnez O, Naya I, Garca-Honduvilla N, lvarez-Mon M, Bujn J, et al
As a double-board certified plastic surgeon, Dr
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Bertilsson et al
One key difference between the two is how they work: Tirzepatide is a dual agonist, which means it affects two different pathways, GLP-1 and GIP, whereas semaglutide only affects GLP-1
Sanyal and other experts have suggested that people who have already progressed to advanced fibrosis or cirrhosis may also need liver-directed therapies, such as Rezdiffra (a selective thyroid hormone receptor-beta agonist) or one of the many medications in the MASLD/MASH pipeline, to reverse existing liver scarring
