what is oral melanotic macule Clinical features of oral pigmented
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In some series, more than 50% of patients with the tumor have evidence of Carney complex , which includes myxomas of the heart, skin, and breast, spotty pigmentation caused by lentigenes, blue nevus and the distinctive epithelioid blue nevus, endocrine overactivity manifested by Cushing disease (pigmented nodular adrenal disease), acromegaly (pituitary adenoma), or sexual precocity (Sertoli cell tumor)

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3 Although it may arise from a congenital nest of melanocytes, a choroidal nevus may not become pigmented or clinically evident until puberty or young adulthood
