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The therapeutic effects of these compounds in animal models and in vitro studies either in delaying motor symptoms, protecting against motor neuron loss and/or improving survival suggest that further studies should be performed to characterize abnormalities in energy metabolism in ALS and explore potential metabolic therapies

Patient benefit: Identifies a treatable trigger (diet, meds, genetic lipid disorders) so you can prevent another attack

Zheng G, Qiu Y, Zhang Q-F, Li D (2014) Chlorogenic acid and caffeine in combination inhibit fat accumulation by regulating hepatic lipid metabolism-related enzymes in mice

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While there are some studies showing it may be good for fat loss, other research suggests otherwise