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However, cells are known to possess inherently poor antioxidant capacity (Lenzen et al., 1996), and this coupled with the lower levels of plasmalogens may result in enhanced susceptibility of cells to metabolic stress and ROS contributing to the autoimmune response

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Thus, the carnitine pool plays a key role in maintaining endocrine homeostasis and metabolic health and provides a new therapeutic strategy for the treatment of some reproductive and metabolic diseases

Supplementary information Supplementary Tables 15, Supplementary Figures 123 and Supplementary Methods (PDF 2144 kb) Rights and permissions About this article Cite this article Koeth, R., Wang, Z., Levison, B