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Limited Long-Term Research There is still limited long-term data on the safety of AOD-9604, especially with extended use

Importantly, cell viability was not affected, meaning the compound did not simply kill fat cells but changed their metabolic behavior

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However, despite encouraging early laboratory findings, its clinical development was discontinued in 2007 after failing to demonstrate significant weight-loss efficacy in large-scale human trials

Bone Fractures In 2019, a study found an association between high intakes of vitamins B6 and B12 from food and supplements with the risk of hip fracture among postmenopausal women in the Harvard Nurses Health Study

Consider complementary NAD+ precursors (NMN/NR) per emerging stack protocols [8]