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In adipose models, reduced NNMT activity has been linked with smaller adipocyte size and diminished fat depots, suggesting a potential role for this inhibitor in fat mass modulation under research conditions

(2016) 83:78591 e1

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Induction of disease LPS On day minus-1, all mice were anesthetized with inhaled isoflurane, and the hair was removed from the dorsal skin using electric clippers followed by depilation with thioglycolate and sodium hydroxide (Nair)

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Avoid exposure to light and repeated freeze-thaw cycles