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Description
doi: 10.1016/j.jddst.2023.104876 178

under ferroptotic conditions, lysosomal leakage releases hydrolytic enzymes and iron-rich contents into the cytosol, amplifying oxidative stress (72)

The net result of manipulating GPx-1 expression on apoptosis will depend on levels of other intracellular antioxidant enzymes

There are several isoenzymes of ALDH with different kinetic and binding parameters that influence acetaldehyde oxidation rates

& Hsieh-Wilson, L

This method has been associated with improved therapeutic outcomes, including longer half-lives and greater efficacy and safety [157, 158]
